Peak serum levels in patients with nephrotic syndrome were reached in 4 hours.
Discontinuation of supplemental calcium and a low-calcium diet are also indicated in accidental overdosage.
Furthermore, the elevation of plasma calcium to normal levels is also required for the functioning of the neuromuscular junction as well as vasodilatation, nerve transmission, and hormonal secretion.
Pharmacokinetics Absorption Calcitriol is rapidly absorbed from the intestine.